Non-culprit lesion revascularization in ST-segment elevation myocardial infarction with multivessel disease

Abstract

Percutaneous coronary intervention (PCI) of the culprit lesion is now considered the gold standard in the treatment for patients with ST-segment elevation myocardial infarction (STEMI). Multivessel coronary artery disease (MVD) is found in approximately 40-65% of patients with STEMI undergoing primary PCI. The optimal reperfusion strategy and timing of revascularization (MV-PCI, S-PCI or IRA-PCI) in hemodynamically stable patients with STEMI and multivessel disease remains uncertain. Recent studies suggest that complete revascularization is superior to culprit-only revascularization in this context. In this review, we summarize the available evidence on treatment options for patients with STEMI and MVD.