Fluoxetinaren eragina Mytilus galloprovincialis muskuiluen gene-adierazpenean eta itu-geneen balizko erabilpena biomarkatzaile gisa

Abstract

Fluoxetine (FLX), besides being one of the most widely used antidepressants, is an emerging pollutant in aquatic environments. FLX can affect the behaviour, reproduction and development of aquatic organisms. To further investigate the molecular effects of FLX, Mytilus galloprovincialis mussels were exposed to FLX and their digestive gland transcriptome was studied after 2, 7, 14 and 28 days. The highest number of significantly regulated sequences were found after 28 days, including changes in genes that encode proteins related to several types of enzymes (hydrolases, transferases and oxidoreductases), membrane and transport across the membrane, as well as energy metabolism.