Kitosano deribatuen nanopartikulak tratamendu oftalmologikoetarako ektoinaren askapen kontrolatuko sistema gisa

Authors

  • Nekane Martin-Mendia i+Med S: Coop. + EHU/UPV
  • Virginia Sáez-Martinez i+Med S. Coop.
  • Jose Luis Pedraz University of the Basque Country (UPV/EHU)
  • Oihane Gartziandia i+Med S. Coop.

DOI:

https://doi.org/10.26876/ikergazte.vi.04.21

Keywords:

nanoparticle, chitosan, controlled-release, ophthalmology

Abstract

The use of nanoparticles as a controlled release platform is a field of research of great interest. This work optimizes the synthesis of different nanoparticles with quaternary ammonium derivatives obtained by controlling the functionalization degree of chitosan. These particles have improved properties, including a greater mucoadhesion to biological tissues. Nanoparticles of 100-300nm are obtained, both empty and loaded with active ingredients using chitosan and its derivatives. In particular, the potential of these nanoparticles in the treatment of eye diseases is analized by investigating the encapsulated ectoine release profile.

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Copyright (c) 2025 IkerGazte. Nazioarteko ikerketa euskaraz

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

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Published

2025-05-30

How to Cite

Martin-Mendia, N., Sáez-Martinez, V., Luis Pedraz, J., & Gartziandia, O. (2025). Kitosano deribatuen nanopartikulak tratamendu oftalmologikoetarako ektoinaren askapen kontrolatuko sistema gisa. IkerGazte. Nazioarteko Ikerketa Euskaraz, 4, 177–284. https://doi.org/10.26876/ikergazte.vi.04.21

Conference Proceedings Volume

Vol. 4 (2025): VI. Ikergazte. Nazioarteko ikerketa euskaraz. Kongresuko artikulu bilduma.Osasun Zientziak

Section

Artikuluak

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