Omega-3 gantz-azidoek nerabezaroko alkoholaren ondorioak arintzen dituzte hipokanpoko sistema endokannabinoidean

Abstract

Alcohol is the most widely consumed psychoactive substance, and its abuse during adolescence can have severe and long-lasting effects on the brain, particularly in the hippocampus. Alcohol disrupts the endocannabinoid system, which neurons use for communication, especially the cannabinoid CB1 receptor. Omega-3 fatty acids enhance neuronal communication and support the function of the endocannabinoid system. This study examines the effects of adolescent alcohol intake on hippocampal CB1 receptors and assesses the potential benefits of an omega-3-enriched diet. The results suggest that omega-3 fatty acids may help mitigate alcohol-induced damage, emphasizing their potential as a nonpharmacological therapeutic approach.