Ardiaren 21 ehunetan karakterizatutako eta kuantifikatutako miRNA molekulen adierazpenaren banaketaren azterketa

Authors

  • Martin Bilbao-Arribas University of Navarra
  • Aitor Guisasola-Serrano Euskal Herriko Unibertsitatea/Universidad del País Vasco
  • Endika Varela-Martínez University of the Basque Country (UPV/EHU)
  • Laura Diez-Fuentes University of the Basque Country (UPV/EHU)
  • Begoña Marina Jugo Euskal Herriko Unibertsitatea/Universidad del País Vasco

DOI:

https://doi.org/10.26876/ikergazte.v.05.28

Keywords:

miRNA, miRNA-seq, expression, ruminant, tissue-specific

Abstract

MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs that regulate gene expression. In sheep, few miRNAs have been described compared with other livestock species. We uniformly analyzed 172 public ovine miRNA-seq datasets from 21 different tissues in order to predict conserved and novel miRNA precursors and profile their expression patterns. 270 miRNAs showed high tissue specificity index values. Strikingly, over 100 precursors from the ruminant-specific family of mir- 2284/mir-2285 miRNAs were found. This work supports the known high evolutionary conservation of many miRNAs, but also highlights the potential of clade-specific innovations in ruminant evolution.

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Copyright (c) 2023 IkerGazte. Nazioarteko ikerketa euskaraz

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This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

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Published

2023-05-09

How to Cite

Bilbao-Arribas, M., Guisasola-Serrano, A., Varela-Martínez, E., Diez-Fuentes, L., & Marina Jugo, B. (2023). Ardiaren 21 ehunetan karakterizatutako eta kuantifikatutako miRNA molekulen adierazpenaren banaketaren azterketa. IkerGazte. Nazioarteko Ikerketa Euskaraz, 5, 225–232. https://doi.org/10.26876/ikergazte.v.05.28

Conference Proceedings Volume

Vol. 5 (2023): V. Ikergazte. Nazioarteko ikerketa euskaraz. Kongresuko artikulu bilduma. Zientziak eta Natura Zientziak

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Artikuluak

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